Protein Cripto

BE0012740ProteinHumansCRIPTO

GPI-anchored cell membrane protein involved in Nodal signaling. It is acted on by 1 drug in DrugBank.

Gene name
CRIPTO
UniProtKB entry
P13385Swiss-Prot
Cellular location
Cell membrane
Residues / weight
188 residues · 21,168 Da
Also known as
CRGF · CRIPTO-1 · Cripto-1 growth factor · Cripto, EGF-CFC family member · Epidermal growth factor-like cripto protein CR1

Resolves to

Protein
UniProtP13385UniProt nameTDGF1_HUMAN
Gene
HGNCHGNC:11701NCBI Gene6997GeneCardsCRIPTO
Pharmacology
KEGGhsa:6997
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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33GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Protein Cripto, and which indications are they being tested in?

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