Integrin beta-5

BE0012746ProteinHumansITGB5

Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It is acted on by 5 drugs in DrugBank.

Gene name
ITGB5
UniProtKB entry
P18084Swiss-Prot
Cellular location
Cell membrane
Residues / weight
799 residues · 88,053 Da

Resolves to

Protein
UniProtP18084UniProt nameITB5_HUMAN
Gene
HGNCHGNC:6160NCBI Gene3693GeneCardsITGB5
Pharmacology
IUPHAR/GtoPdb2459KEGGhsa:3693
Structure
PDB7S46PDB7S47PDB7S48
Drugs

What you can answer from here — as of September 03, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Integrin beta-5, and which indications are they being tested in?

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