Myelin-associated glycoprotein

BE0012799ProteinHumansMAG

Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
MAG
UniProtKB entry
P20916Swiss-Prot
Cellular location
Cell membrane
Residues / weight
626 residues · 69,068 Da
Also known as
GMA · Siglec-4a

Resolves to

Protein
UniProtP20916UniProt nameMAG_HUMAN
Gene
HGNCHGNC:6783NCBI Gene4099GeneCardsMAG
Pharmacology
KEGGhsa:4099
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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24GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Myelin-associated glycoprotein, and which indications are they being tested in?

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