SHC-transforming protein 1

BE0012847ProteinHumansSHC1

Signaling adapter that couples activated growth factor receptors to signaling pathways. It is acted on by 1 drug in DrugBank.

Gene name
SHC1
UniProtKB entry
P29353Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
583 residues · 62,822 Da
Also known as
SH2 domain protein C1 · SHC · SHC-transforming protein 3 · SHC-transforming protein A · SHCA

Resolves to

Protein
UniProtP29353UniProt nameSHC1_HUMAN
Gene
HGNCHGNC:10840NCBI Gene6464GeneCardsSHC1
Pharmacology
KEGGhsa:6464
Structure
PDB1MILPDB1N3HPDB1OY2
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on SHC-transforming protein 1, how selective are they, and which programs against it are still in active trials?

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