Myelin protein P0

BE0012853ProteinHumansMPZ

Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It is acted on by 1 drug in DrugBank.

Gene name
MPZ
UniProtKB entry
P25189Swiss-Prot
Cellular location
Cell membrane
Residues / weight
248 residues · 27,555 Da
Also known as
MPP · Myelin peripheral protein · Myelin protein zero

Resolves to

Protein
UniProtP25189UniProt nameMYP0_HUMAN
Gene
HGNCHGNC:7225NCBI Gene4359GeneCardsMPZ
Pharmacology
KEGGhsa:4359
Structure
PDB3OAIPDB8IIA
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Myelin protein P0, and which indications are they being tested in?

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