3-mercaptopyruvate sulfurtransferase

BE0012863ProteinHumansMPST

Transfer of a sulfur ion to cyanide or to other thiol compounds. It is acted on by 2 drugs in DrugBank.

Gene name
MPST
UniProtKB entry
P25325Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
297 residues · 33,178 Da
Also known as
2.8.1.2 · MST · TST2

Resolves to

Protein
UniProtP25325UniProt nameTHTM_HUMAN
Gene
HGNCHGNC:7223NCBI Gene4357GeneCardsMPST
Pharmacology
IUPHAR/GtoPdb1446KEGGhsa:4357
Structure
PDB3OLHPDB4JGT
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 3-mercaptopyruvate sulfurtransferase, how selective are they, and which programs against it are still in active trials?

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