Midkine

BE0012864ProteinHumansMDK

Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors (PubMed:10212223, PubMed:10772929, PubMed:12084985, PubMed:12122009, PubMed:12573468, PubMed:15466886, PubMed:18469519, PubMed:24458438). It is acted on by 1 drug in DrugBank.

Gene name
MDK
UniProtKB entry
P21741Swiss-Prot
Cellular location
Secreted
Residues / weight
143 residues · 15,585 Da
Also known as
Amphiregulin-associated protein · ARAP · Midgestation and kidney protein · MK · MK1

Resolves to

Protein
UniProtP21741UniProt nameMK_HUMAN
Gene
HGNCHGNC:6972NCBI Gene4192GeneCardsMDK
Pharmacology
KEGGhsa:4192
Structure
PDB1MKCPDB1MKN
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
62GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which compounds in development act on Midkine, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In