Integrin beta-8

BE0012912ProteinHumansITGB8

Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (PubMed:1918072). It is acted on by 1 drug in DrugBank.

Gene name
ITGB8
UniProtKB entry
P26012Swiss-Prot
Cellular location
Cell membrane
Residues / weight
769 residues · 85,631 Da

Resolves to

Protein
UniProtP26012UniProt nameITB8_HUMAN
Gene
HGNCHGNC:6163NCBI Gene3696GeneCardsITGB8
Pharmacology
IUPHAR/GtoPdb2462KEGGhsa:3696
Structure
PDB6DJPPDB6OM1PDB6OM2
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Integrin beta-8, and which indications are they being tested in?

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