Eukaryotic translation initiation factor 4B

BE0012921ProteinHumansEIF4B

Required for the binding of mRNA to ribosomes. It is acted on by 1 drug in DrugBank.

Gene name
EIF4B
UniProtKB entry
P23588Swiss-Prot
Residues / weight
611 residues · 69,150 Da
Also known as
eIF-4B

Resolves to

Protein
UniProtP23588UniProt nameIF4B_HUMAN
Gene
HGNCHGNC:3285NCBI Gene1975GeneCardsEIF4B
Pharmacology
KEGGhsa:1975
Structure
PDB1WI8PDB2J76PDB6FEC
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Eukaryotic translation initiation factor 4B, and which indications are they being tested in?

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