T-cell differentiation antigen CD6

BE0012939ProteinHumansCD6

Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703, PubMed:15294938, PubMed:16352806, PubMed:16914752, PubMed:24584089, PubMed:24945728). It is acted on by 1 drug in DrugBank.

Gene name
CD6
UniProtKB entry
P30203Swiss-Prot
Cellular location
Cell membrane
Residues / weight
668 residues · 71,800 Da
Also known as
T12 · TP120

Resolves to

Protein
UniProtP30203UniProt nameCD6_HUMAN
Gene
HGNCHGNC:1691NCBI Gene923GeneCardsCD6
Pharmacology
IUPHAR/GtoPdb2917KEGGhsa:923
Structure
PDB5A2E
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on T-cell differentiation antigen CD6, and which indications are they being tested in?

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