M-phase inducer phosphatase 1

BE0012947ProteinHumansCDC25A

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression (PubMed:12676925, PubMed:14559997, PubMed:1836978, PubMed:20360007). It is acted on by 1 drug in DrugBank.

Gene name
CDC25A
UniProtKB entry
P30304Swiss-Prot
Residues / weight
524 residues · 59,086 Da
Also known as
3.1.3.48 · Dual specificity phosphatase Cdc25A

Resolves to

Protein
UniProtP30304UniProt nameMPIP1_HUMAN
Gene
HGNCHGNC:1725NCBI Gene993GeneCardsCDC25A
Pharmacology
KEGGhsa:993
Structure
PDB1C25PDB8ROZ
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on M-phase inducer phosphatase 1, and which indications are they being tested in?

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