Kinesin-1 heavy chain

BE0013000ProteinHumansKIF5B

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. It is acted on by 1 drug in DrugBank.

Gene name
KIF5B
UniProtKB entry
P33176Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
963 residues · 109,684 Da
Also known as
Conventional kinesin heavy chain · KNS · KNS1 · Ubiquitous kinesin heavy chain · UKHC

Resolves to

Protein
UniProtP33176UniProt nameKINH_HUMAN
Gene
HGNCHGNC:6324NCBI Gene3799GeneCardsKIF5B
Pharmacology
KEGGhsa:3799
Structure
PDB1BG2PDB1MKJPDB2P4N
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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37GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Kinesin-1 heavy chain, and which indications are they being tested in?

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