Transcriptional enhancer factor TEF-1

BE0013108ProteinHumansTEAD1

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. It is acted on by 1 drug in DrugBank.

Gene name
TEAD1
UniProtKB entry
P28347Swiss-Prot
Cellular location
Nucleus
Residues / weight
426 residues · 47,945 Da
Also known as
NTEF-1 · Protein GT-IIC · TCF-13 · TCF13 · TEA domain family member 1

Resolves to

Protein
UniProtP28347UniProt nameTEAD1_HUMAN
Gene
HGNCHGNC:11714NCBI Gene7003GeneCardsTEAD1
Pharmacology
IUPHAR/GtoPdb3240KEGGhsa:7003
Structure
PDB2HZDPDB3KYSPDB4RE1
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
18GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
5+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Transcriptional enhancer factor TEF-1, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In