Vasoactive intestinal polypeptide receptor 2

BE0013151ProteinHumansVIPR2

G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:7811244, PubMed:35477937, PubMed:8933357). It is acted on by 1 drug in DrugBank.

Gene name
VIPR2
UniProtKB entry
P41587Swiss-Prot
Cellular location
Cell membrane
Residues / weight
438 residues · 49,478 Da
Also known as
Helodermin-preferring VIP receptor · PACAP type III receptor · PACAP-R-3 · PACAP-R3 · Pituitary adenylate cyclase-activating polypeptide type III receptor

Resolves to

Protein
UniProtP41587UniProt nameVIPR2_HUMAN
Gene
HGNCHGNC:12695NCBI Gene7434GeneCardsVIPR2
Pharmacology
IUPHAR/GtoPdb372KEGGhsa:7434
Structure
PDB2X57PDB7VQXPDB7WBJ
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Vasoactive intestinal polypeptide receptor 2, and which indications are they being tested in?

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