5-formyltetrahydrofolate cyclo-ligase

BE0013315ProteinHumansMTHFS

Contributes to tetrahydrofolate metabolism.

Gene name
MTHFS
UniProtKB entry
P49914Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
203 residues · 23,255 Da
Also known as
5,10-methenyl-tetrahydrofolate synthetase · 6.3.3.2 · Methenyl-THF synthetase · MTHFS

Resolves to

Protein
UniProtP49914UniProt nameMTHFS_HUMAN
Gene
HGNCHGNC:7437NCBI Gene10588GeneCardsMTHFS
Pharmacology
KEGGhsa:10588
Structure
PDB3HXTPDB3HY3PDB3HY4

What you can answer from here — as of September 03, 2024

1Metabolic reactionDrug transformations it catalyses, substrate to product
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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Which compounds in development act on 5-formyltetrahydrofolate cyclo-ligase, and which indications are they being tested in?

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