C-C chemokine receptor type 3

BE0013339ProteinHumansCCR3

G protein-coupled receptor (GPCR) that plays a key role in the immune system by regulating the migration and activation of white blood cells in response to chemokines (PubMed:28994588). It is acted on by 2 drugs in DrugBank.

Gene name
CCR3
UniProtKB entry
P51677Swiss-Prot
Cellular location
Cell membrane
Residues / weight
355 residues · 41,043 Da
Also known as
C C CKR3 · C-C CKR-3 · CC-CKR-3 · CCR-3 · CCR3

Resolves to

Protein
UniProtP51677UniProt nameCCR3_HUMAN
Gene
HGNCHGNC:1604NCBI Gene1232GeneCardsCCR3
Pharmacology
IUPHAR/GtoPdb60KEGGhsa:1232
Structure
PDB7X9Y
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on C-C chemokine receptor type 3, and which indications are they being tested in?

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