Protoporphyrinogen oxidase
Details
- Name
- Protoporphyrinogen oxidase
- Kind
- protein
- Synonyms
- 1.3.3.4
- PPO
- Gene Name
- PPOX
- UniProtKB Entry
- P50336Swiss-Prot
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0017745|Protoporphyrinogen oxidase MGRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPRG IRPAGALGARTLLLVSELGLDSEVLPVRGDHPAAQNRFLYVGGALHALPTGLRGLLRPSP PFSKPLFWAGLRELTKPRGKEPDETVHSFAQRRLGPEVASLAMDSLCRGVFAGNSRELSI RSCFPSLFQAEQTHRSILLGLLLGAGRTPQPDSALIRQALAERWSQWSLRGGLEMLPQAL ETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAIPASVLSELLPAEAA PLARALSAITAVSVAVVNLQYQGAHLPVQGFGHLVPSSEDPGVLGIVYDSVAFPEQDGSP PGLRVTVMLGGSWLQTLEASGCVLSQELFQQRAQEAAATQLGLKEMPSHCLVHLHKNCIP QYTLGHWQKLESARQFLTAHRLPLTLAGASYEGVAVNDCIESGRQAAVSVLGTEPNS
- Number of residues
- 477
- Molecular Weight
- 50764.8
- Theoretical pI
- Not Available
- GO Classification
- Not Available
- General Function
- Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
- Specific Function
- flavin adenine dinucleotide binding
- Pfam Domain Function
- Amino_oxidase (PF01593)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion inner membrane
- Gene sequence
- Not Available
- Chromosome Location
- 1
- Locus
- 1q23.3
- External Identifiers
Resource Link UniProtKB ID P50336 UniProtKB Entry Name PPOX_HUMAN GeneCard ID PPOX HGNC ID HGNC:9280 PDB ID(s) 3NKS, 4IVM, 4IVO KEGG ID hsa:5498 NCBI Gene ID 5498 - General References
- Not Available
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Aminolevulinic acid approved yes target modulator Details