ETS translocation variant 1

BE0013390ProteinHumansETV1

Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (PubMed:7651741). It is acted on by 1 drug in DrugBank.

Gene name
ETV1
UniProtKB entry
P50549Swiss-Prot
Cellular location
Nucleus
Residues / weight
477 residues · 55,130 Da
Also known as
ER81 · Ets-related protein 81

Resolves to

Protein
UniProtP50549UniProt nameETV1_HUMAN
Gene
HGNCHGNC:3490NCBI Gene2115GeneCardsETV1
Pharmacology
KEGGhsa:2115
Structure
PDB4AVPPDB4BNCPDB5ILS
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on ETS translocation variant 1, and which indications are they being tested in?

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