Dicarboxylate carrier SLC25A8
BE0013557ProteinHumansUCP2
Antiporter that exports dicarboxylate intermediates of the Krebs cycle in exchange for phosphate plus a proton across the inner membrane of mitochondria, a process driven by mitochondrial motive force with an overall impact on glycolysis,... It is acted on by 1 drug in DrugBank.
- Gene name
- UCP2
- UniProtKB entry
- P55851Swiss-Prot
- Cellular location
- Mitochondrion inner membrane
- Residues / weight
- 309 residues · 33,229 Da
- Also known as
- Mitochondrial uncoupling protein 2 · SLC25A8 · Solute carrier family 25 member 8 · UCP 2 · UCPH
Resolves to
Pharmacology
Drugs
What you can answer from here — as of September 03, 2024
Which compounds in development act on Dicarboxylate carrier SLC25A8, and which indications are they being tested in?
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