Ephrin type-B receptor 3

BE0013598ProteinHumansEPHB3

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

Gene name
EPHB3
UniProtKB entry
P54753Swiss-Prot
Cellular location
Cell membrane
Residues / weight
998 residues · 110,329 Da
Also known as
2.7.10.1 · EK2 · Embryonic kinase 2 · EPH-like kinase 2 · EPH-like tyrosine kinase 2

Resolves to

What you can answer from here — as of September 03, 2024

24GO termsFunction, process and component, as structured annotations
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7Pfam domainsDomain architecture mapped to Pfam families and clans
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Which compounds in development act on Ephrin type-B receptor 3, and which indications are they being tested in?

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