Galactocerebrosidase

BE0013617ProteinHumansGALC

Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine (PubMed:8281145, PubMed:8399327). It is acted on by 1 drug in DrugBank.

Gene name
GALC
UniProtKB entry
P54803Swiss-Prot
Cellular location
Lysosome
Residues / weight
685 residues · 77,063 Da
Also known as
3.2.1.46 · Galactocerebroside beta-galactosidase · Galactosylceramidase · Galactosylceramide beta-galactosidase · GALCERase

Resolves to

Protein
UniProtP54803UniProt nameGALC_HUMAN
Gene
HGNCHGNC:4115NCBI Gene2581GeneCardsGALC
Pharmacology
KEGGhsa:2581
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Galactocerebrosidase, and which indications are they being tested in?

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