Serine/threonine-protein phosphatase 4 catalytic subunit

BE0013727ProteinHumansPPP4C

Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone... It is acted on by 1 drug in DrugBank.

Gene name
PPP4C
UniProtKB entry
P60510Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
307 residues · 35,080 Da
Also known as
3.1.3.16 · PP-X · Pp4 · PP4C · PPP4

Resolves to

Protein
UniProtP60510UniProt namePP4C_HUMAN
Gene
HGNCHGNC:9319NCBI Gene5531GeneCardsPPP4C
Pharmacology
KEGGhsa:5531
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Serine/threonine-protein phosphatase 4 catalytic subunit, and which indications are they being tested in?

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