Dipeptidyl peptidase 1

BE0013736ProteinHumansCTSC

Thiol protease (PubMed:1586157). It is acted on by 1 drug in DrugBank.

Gene name
CTSC
UniProtKB entry
P53634Swiss-Prot
Cellular location
Lysosome
Residues / weight
463 residues · 51,853 Da
Also known as
3.4.14.1 · Cathepsin C · Cathepsin J · CPPI · Dipeptidyl peptidase I

Resolves to

Protein
UniProtP53634UniProt nameCATC_HUMAN
Gene
HGNCHGNC:2528NCBI Gene1075GeneCardsCTSC
Pharmacology
IUPHAR/GtoPdb2344KEGGhsa:1075
Structure
PDB1K3BPDB2DJFPDB2DJG
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Dipeptidyl peptidase 1, how selective are they, and which programs against it are still in active trials?

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