Oligodendrocyte transcription factor 2

BE0014194ProteinHumansOLIG2

Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. It is acted on by 1 drug in DrugBank.

Gene name
OLIG2
UniProtKB entry
Q13516Swiss-Prot
Cellular location
Nucleus
Residues / weight
323 residues · 32,384 Da
Also known as
BHLHB1 · BHLHE19 · Class B basic helix-loop-helix protein 1 · Class E basic helix-loop-helix protein 19 · Oligo2

Resolves to

Protein
UniProtQ13516UniProt nameOLIG2_HUMAN
Gene
HGNCHGNC:9398NCBI Gene10215GeneCardsOLIG2
Pharmacology
KEGGhsa:10215
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Oligodendrocyte transcription factor 2, and which indications are they being tested in?

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