CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

BE0014271ProteinHumansST3GAL4

A beta-galactoside alpha2-3 sialyltransferase involved in terminal sialylation of glycoproteins and glycolipids (PubMed:8288606, PubMed:8611500, PubMed:37632720). It is acted on by 1 drug in DrugBank.

Gene name
ST3GAL4
UniProtKB entry
Q11206Swiss-Prot
Cellular location
Golgi apparatus, Golgi stack membrane
Residues / weight
333 residues · 38,045 Da
Also known as
2.4.3.2 · 2.4.3.4 · Alpha 2,3-sialyltransferase IV · Alpha 2,3-ST 4 · Beta-galactoside alpha-2,3-sialyltransferase 4

Resolves to

Protein
UniProtQ11206UniProt nameSIA4C_HUMAN
Gene
HGNCHGNC:10864NCBI Gene6484GeneCardsST3GAL4
Pharmacology
KEGGhsa:6484
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4, and which indications are they being tested in?

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