Inositol-tetrakisphosphate 1-kinase

BE0014272ProteinHumansITPK1

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 (PubMed:11042108, PubMed:8662638). It is acted on by 1 drug in DrugBank.

Gene name
ITPK1
UniProtKB entry
Q13572Swiss-Prot
Residues / weight
414 residues · 45,621 Da
Also known as
2.7.1.134 · Inositol 1,3,4-trisphosphate 5/6-kinase · Inositol-triphosphate 5/6-kinase · Ins(1,3,4)P(3) 5/6-kinase

Resolves to

Protein
UniProtQ13572UniProt nameITPK1_HUMAN
Gene
HGNCHGNC:6177NCBI Gene3705GeneCardsITPK1
Pharmacology
KEGGhsa:3705
Structure
PDB2ODTPDB2Q7DPDB2QB5
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Inositol-tetrakisphosphate 1-kinase, and which indications are they being tested in?

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