Lysyl oxidase homolog 1

BE0014332ProteinHumansLOXL1

Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
LOXL1
UniProtKB entry
Q08397Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
574 residues · 63,109 Da
Also known as
1.4.3.13 · LOL · LOXL · Lysyl oxidase-like protein 1

Resolves to

Protein
UniProtQ08397UniProt nameLOXL1_HUMAN
Gene
HGNCHGNC:6665NCBI Gene4016GeneCardsLOXL1
Pharmacology
KEGGhsa:4016
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Lysyl oxidase homolog 1, and which indications are they being tested in?

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