Interleukin-10 receptor subunit alpha

BE0014391ProteinHumansIL10RA

Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. It is acted on by 3 drugs in DrugBank.

Gene name
IL10RA
UniProtKB entry
Q13651Swiss-Prot
Cellular location
Cell membrane
Residues / weight
578 residues · 63,002 Da
Also known as
CDw210a · IL-10 receptor subunit alpha · IL-10R subunit 1 · IL-10R subunit alpha · IL-10R1

Resolves to

Protein
UniProtQ13651UniProt nameI10R1_HUMAN
Gene
HGNCHGNC:5964NCBI Gene3587GeneCardsIL10RA
Pharmacology
IUPHAR/GtoPdb1727KEGGhsa:3587
Structure
PDB1J7VPDB1LQSPDB1Y6K
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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20GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interleukin-10 receptor subunit alpha, and which indications are they being tested in?

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