CD166 antigen

BE0014432ProteinHumansALCAM

Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts (PubMed:15048703, PubMed:15496415, PubMed:16352806, PubMed:23169771, PubMed:24945728, PubMed:7760007). It is acted on by 1 drug in DrugBank.

Gene name
ALCAM
UniProtKB entry
Q13740Swiss-Prot
Cellular location
Cell membrane
Residues / weight
583 residues · 65,102 Da
Also known as
Activated leukocyte cell adhesion molecule · MEMD

Resolves to

Protein
UniProtQ13740UniProt nameCD166_HUMAN
Gene
HGNCHGNC:400NCBI Gene214GeneCardsALCAM
Pharmacology
KEGGhsa:214
Structure
PDB5A2F
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on CD166 antigen, and which indications are they being tested in?

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