Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

BE0014503ProteinHumansPPP2R5D

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment. It is acted on by 1 drug in DrugBank.

Gene name
PPP2R5D
UniProtKB entry
Q14738Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
602 residues · 69,991 Da
Also known as
PP2A B subunit isoform B'-delta · PP2A B subunit isoform B56-delta · PP2A B subunit isoform PR61-delta · PP2A B subunit isoform R5-delta

Resolves to

Protein
UniProtQ14738UniProt name2A5D_HUMAN
Gene
HGNCHGNC:9312NCBI Gene5528GeneCardsPPP2R5D
Pharmacology
KEGGhsa:5528
Structure
PDB8U1XPDB8U89
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, and which indications are they being tested in?

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