Transcriptional enhancer factor TEF-3

BE0014570ProteinHumansTEAD4

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. It is acted on by 1 drug in DrugBank.

Gene name
TEAD4
UniProtKB entry
Q15561Swiss-Prot
Cellular location
Nucleus
Residues / weight
434 residues · 48,328 Da
Also known as
RTEF1 · TCF13L1 · TEA domain family member 4 · TEAD-4 · TEF3

Resolves to

Protein
UniProtQ15561UniProt nameTEAD4_HUMAN
Gene
HGNCHGNC:11717NCBI Gene7004GeneCardsTEAD4
Pharmacology
IUPHAR/GtoPdb3243KEGGhsa:7004
Structure
PDB5GZBPDB5NO6PDB5OAQ
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Transcriptional enhancer factor TEF-3, and which indications are they being tested in?

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