Myosin-binding protein C, cardiac-type

BE0014590ProteinHumansMYBPC3

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. It is acted on by 2 drugs in DrugBank.

Gene name
MYBPC3
UniProtKB entry
Q14896Swiss-Prot
Residues / weight
1,274 residues · 140,761 Da
Also known as
C-protein, cardiac muscle isoform · Cardiac MyBP-C

Resolves to

Protein
UniProtQ14896UniProt nameMYPC3_HUMAN
Gene
HGNCHGNC:7551NCBI Gene4607GeneCardsMYBPC3
Pharmacology
KEGGhsa:4607
Structure
PDB1GXEPDB1PD6PDB2AVG
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Myosin-binding protein C, cardiac-type, how selective are they, and which programs against it are still in active trials?

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