Plectin

BE0014616ProteinHumansPLEC

Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. It is acted on by 1 drug in DrugBank.

Gene name
PLEC
UniProtKB entry
Q15149Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
4,684 residues · 531,786 Da
Also known as
HD1 · Hemidesmosomal protein 1 · PCN · PLEC1 · Plectin-1

Resolves to

Protein
UniProtQ15149UniProt namePLEC_HUMAN
Gene
HGNCHGNC:9069NCBI Gene5339GeneCardsPLEC
Pharmacology
KEGGhsa:5339
Structure
PDB1MB8PDB2N03PDB2ODU
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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57GO termsFunction, process and component, as structured annotations
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8Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Plectin, and which indications are they being tested in?

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