Sigma intracellular receptor 2
BE0015084ProteinHumansTMEM97
Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the maintenance... It is acted on by 5 drugs in DrugBank.
- Gene name
- TMEM97
- UniProtKB entry
- Q5BJF2Swiss-Prot
- Cellular location
- Rough endoplasmic reticulum membrane
- Residues / weight
- 176 residues · 20,848 Da
- Also known as
- MAC30 · Meningioma-associated protein 30 · S2R · Sigma-2 receptor · Sigma2 receptor
Resolves to
Pharmacology
Drugs
What you can answer from here — as of September 03, 2024
Which compounds in development act on Sigma intracellular receptor 2, and which indications are they being tested in?
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