Lysine-specific demethylase 4D

BE0015193ProteinHumansKDM4D

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It is acted on by 1 drug in DrugBank.

Gene name
KDM4D
UniProtKB entry
Q6B0I6Swiss-Prot
Cellular location
Nucleus
Residues / weight
523 residues · 58,602 Da
Also known as
[histone H3]-trimethyl-L-lysine(9) demethylase 4D · 1.14.11.66 · JHDM3D · JmjC domain-containing histone demethylation protein 3D · JMJD2D

Resolves to

Protein
UniProtQ6B0I6UniProt nameKDM4D_HUMAN
Gene
HGNCHGNC:25498NCBI Gene55693GeneCardsKDM4D
Pharmacology
KEGGhsa:55693
Structure
PDB3DXTPDB3DXUPDB4D6Q
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Lysine-specific demethylase 4D, and which indications are they being tested in?

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