Sodium-dependent neutral amino acid transporter B(0)AT1

BE0015577ProteinHumansSLC6A19

Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells (PubMed:15286787, PubMed:15286788, PubMed:18424768, PubMed:18484095, PubMed:19185582, PubMed:26240152). It is acted on by 2 drugs in DrugBank.

Gene name
SLC6A19
UniProtKB entry
Q695T7Swiss-Prot
Cellular location
Cell membrane
Residues / weight
634 residues · 71,109 Da
Also known as
B0AT1 · Solute carrier family 6 member 19 · System B(0) neutral amino acid transporter AT1

Resolves to

Protein
UniProtQ695T7UniProt nameS6A19_HUMAN
Gene
HGNCHGNC:27960NCBI Gene340024GeneCardsSLC6A19
Pharmacology
IUPHAR/GtoPdb939KEGGhsa:340024
Structure
PDB6M17PDB6M18PDB6M1D
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sodium-dependent neutral amino acid transporter B(0)AT1, and which indications are they being tested in?

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