Chondroitin sulfate proteoglycan 4

BE0015621ProteinHumansCSPG4

Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. It is acted on by 1 drug in DrugBank.

Gene name
CSPG4
UniProtKB entry
Q6UVK1Swiss-Prot
Cellular location
Cell membrane
Residues / weight
2,322 residues · 250,535 Da
Also known as
Chondroitin sulfate proteoglycan NG2 · MCSP · Melanoma chondroitin sulfate proteoglycan · Melanoma-associated chondroitin sulfate proteoglycan

Resolves to

Protein
UniProtQ6UVK1UniProt nameCSPG4_HUMAN
Gene
HGNCHGNC:2466NCBI Gene1464GeneCardsCSPG4
Pharmacology
KEGGhsa:1464
Structure
PDB7ML7PDB7N8XPDB7N9Y
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Chondroitin sulfate proteoglycan 4, and which indications are they being tested in?

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