PHD finger-like domain-containing protein 5A

BE0016305ProteinHumansPHF5A

Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:12234937, PubMed:27720643, PubMed:28541300, PubMed:32494006, PubMed:34822310). It is acted on by 1 drug in DrugBank.

Gene name
PHF5A
UniProtKB entry
Q7RTV0Swiss-Prot
Cellular location
Nucleus
Residues / weight
110 residues · 12,405 Da
Also known as
PHD finger-like domain protein 5A · SF3b14b · Splicing factor 3B-associated 14 kDa protein

Resolves to

Protein
UniProtQ7RTV0UniProt namePHF5A_HUMAN
Gene
HGNCHGNC:18000NCBI Gene84844GeneCardsPHF5A
Pharmacology
KEGGhsa:84844
Structure
PDB5IFEPDB5O9ZPDB5SYB
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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22GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on PHD finger-like domain-containing protein 5A, and which indications are they being tested in?

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