Dipeptidyl peptidase 9

BE0016313ProteinHumansDPP9

Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2 (PubMed:12662155, PubMed:16475979, PubMed:19667070, PubMed:29382749, PubMed:30291141, PubMed:33731929, PubMed:36112693). It is acted on by 1 drug in DrugBank.

Gene name
DPP9
UniProtKB entry
Q86TI2Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
863 residues · 98,263 Da
Also known as
3.4.14.5 · Dipeptidyl peptidase IV-related protein 2 · Dipeptidyl peptidase IX · Dipeptidyl peptidase-like protein 9 · DP9

Resolves to

Protein
UniProtQ86TI2UniProt nameDPP9_HUMAN
Gene
HGNCHGNC:18648NCBI Gene91039GeneCardsDPP9
Pharmacology
IUPHAR/GtoPdb2357KEGGhsa:91039
Structure
PDB6EOQPDB6EORPDB6QZV
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dipeptidyl peptidase 9, and which indications are they being tested in?

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