Interferon lambda receptor 1

BE0016547ProteinHumansIFNLR1

The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. It is acted on by 1 drug in DrugBank.

Gene name
IFNLR1
UniProtKB entry
Q8IU57Swiss-Prot
Cellular location
Membrane
Residues / weight
520 residues · 57,652 Da
Also known as
CRF2-12 · Cytokine receptor class-II member 12 · Cytokine receptor family 2 member 12 · IFN-lambda receptor 1 · IFN-lambda-R1

Resolves to

Protein
UniProtQ8IU57UniProt nameINLR1_HUMAN
Gene
HGNCHGNC:18584NCBI Gene163702GeneCardsIFNLR1
Pharmacology
KEGGhsa:163702
Structure
PDB3OG4PDB3OG6PDB5IXD
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interferon lambda receptor 1, and which indications are they being tested in?

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