TIR domain-containing adapter molecule 1

BE0016552ProteinHumansTICAM1

Involved in innate immunity against invading pathogens. It is acted on by 1 drug in DrugBank.

Gene name
TICAM1
UniProtKB entry
Q8IUC6Swiss-Prot
Cellular location
Cytoplasmic vesicle, autophagosome
Residues / weight
712 residues · 76,421 Da
Also known as
MyD88-3 · Proline-rich, vinculin and TIR domain-containing protein B · PRVTIRB · Putative NF-kappa-B-activating protein 502H · TICAM-1

Resolves to

Protein
UniProtQ8IUC6UniProt nameTCAM1_HUMAN
Gene
HGNCHGNC:18348NCBI Gene148022GeneCardsTICAM1
Pharmacology
KEGGhsa:148022
Structure
PDB2M1XPDB2M63PDB3RC4
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on TIR domain-containing adapter molecule 1, and which indications are they being tested in?

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