Transmembrane protease serine 6

BE0016559ProteinHumansTMPRSS6

Membrane-bound serine protease (PubMed:18976966, PubMed:20518742, PubMed:25156943, PubMed:25588876). It is acted on by 1 drug in DrugBank.

Gene name
TMPRSS6
UniProtKB entry
Q8IU80Swiss-Prot
Cellular location
Cell membrane
Residues / weight
811 residues · 89,999 Da
Also known as
3.4.21.- · Matriptase-2

Resolves to

Protein
UniProtQ8IU80UniProt nameTMPS6_HUMAN
Gene
HGNCHGNC:16517NCBI Gene164656GeneCardsTMPRSS6
Pharmacology
IUPHAR/GtoPdb2422KEGGhsa:164656
Structure
PDB9NRC
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Transmembrane protease serine 6, and which indications are they being tested in?

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