C-type lectin domain family 10 member A

BE0016623ProteinHumansCLEC10A

C-type lectin receptor involved in recognition of N-acetylgalactosamine (GalNAc)-terminated glycans by myeloid antigen presenting cells (APCs) (PubMed:15802303, PubMed:16998493, PubMed:17616966, PubMed:22213806, PubMed:33724805, PubMed:8598452). It is acted on by 1 drug in DrugBank.

Gene name
CLEC10A
UniProtKB entry
Q8IUN9Swiss-Prot
Cellular location
Cell membrane
Residues / weight
316 residues · 35,446 Da
Also known as
C-type lectin superfamily member 14 · CLECSF13 · CLECSF14 · DC-ASGPR · DC-asialoglycoprotein receptor

Resolves to

Protein
UniProtQ8IUN9UniProt nameCLC10_HUMAN
Gene
HGNCHGNC:16916NCBI Gene10462GeneCardsCLEC10A
Pharmacology
KEGGhsa:10462
Structure
PDB6PUVPDB6PY1PDB6W12
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which compounds in development act on C-type lectin domain family 10 member A, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In