Acyl-coenzyme A diphosphatase FITM2

BE0016640ProteinHumansFITM2

Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity) (PubMed:32915949). It is acted on by 1 drug in DrugBank.

Gene name
FITM2
UniProtKB entry
Q8N6M3Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
262 residues · 29,855 Da
Also known as
3.6.1.- · C20orf142 · Fat storage-inducing transmembrane protein 2 · Fat-inducing protein 2 · FIT2

Resolves to

Protein
UniProtQ8N6M3UniProt nameFITM2_HUMAN
Gene
HGNCHGNC:16135NCBI Gene128486GeneCardsFITM2
Pharmacology
KEGGhsa:128486
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Acyl-coenzyme A diphosphatase FITM2, and which indications are they being tested in?

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