Endonuclease V

BE0016813ProteinHumansENDOV

Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed:23912683, PubMed:23912718, PubMed:25195743, PubMed:27573237, PubMed:31703097). It is acted on by 1 drug in DrugBank.

Gene name
ENDOV
UniProtKB entry
Q8N8Q3Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
282 residues · 30,791 Da
Also known as
3.1.26.- · hEndoV · Inosine-specific endoribonuclease

Resolves to

Protein
UniProtQ8N8Q3UniProt nameENDOV_HUMAN
Gene
HGNCHGNC:26640NCBI Gene284131GeneCardsENDOV
Pharmacology
KEGGhsa:284131
Structure
PDB4NSPPDB6OZE
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
7+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Endonuclease V, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In