Interleukin-17 receptor C

BE0017016ProteinHumansIL17RC

Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
IL17RC
UniProtKB entry
Q8NAC3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
791 residues · 86,239 Da
Also known as
IL-17 receptor C · IL-17RC · IL-17RL · IL17Rhom · Interleukin-17 receptor homolog

Resolves to

Protein
UniProtQ8NAC3UniProt nameI17RC_HUMAN
Gene
HGNCHGNC:18358NCBI Gene84818GeneCardsIL17RC
Pharmacology
KEGGhsa:84818
Structure
PDB6HG4PDB6HG9PDB6HGA
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Interleukin-17 receptor C, how selective are they, and which programs against it are still in active trials?

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