Leukocyte immunoglobulin-like receptor subfamily B member 4

BE0017129ProteinHumansLILRB4

Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance (PubMed:11875462). It is acted on by 2 drugs in DrugBank.

Gene name
LILRB4
UniProtKB entry
Q8NHJ6Swiss-Prot
Cellular location
Cell membrane
Residues / weight
448 residues · 49,355 Da
Also known as
B4 · CD85 antigen-like family member K · ILT-3 · ILT3 · Immunoglobulin-like transcript 3

Resolves to

Protein
UniProtQ8NHJ6UniProt nameLIRB4_HUMAN
Gene
HGNCHGNC:6608NCBI Gene11006GeneCardsLILRB4
Pharmacology
KEGGhsa:11006
Structure
PDB3P2TPDB6K7O
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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41GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Leukocyte immunoglobulin-like receptor subfamily B member 4, and which indications are they being tested in?

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