Interleukin-17 receptor D

BE0017358ProteinHumansIL17RD

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed:12807873, PubMed:12958313). It is acted on by 1 drug in DrugBank.

Gene name
IL17RD
UniProtKB entry
Q8NFM7Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
739 residues · 82,410 Da
Also known as
hSef · IL-17 receptor D · IL-17RD · IL17Rhom · IL17RLM

Resolves to

Protein
UniProtQ8NFM7UniProt nameI17RD_HUMAN
Gene
HGNCHGNC:17616NCBI Gene54756GeneCardsIL17RD
Pharmacology
KEGGhsa:54756
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Interleukin-17 receptor D, how selective are they, and which programs against it are still in active trials?

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