Interleukin-17 receptor A

BE0018249ProteinHumansIL17RA

Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. It is acted on by 1 drug in DrugBank.

Gene name
IL17RA
UniProtKB entry
Q96F46Swiss-Prot
Cellular location
Cell membrane
Residues / weight
866 residues · 96,121 Da
Also known as
CDw217 · IL-17 receptor A · IL-17RA · IL17R

Resolves to

Protein
UniProtQ96F46UniProt nameI17RA_HUMAN
Gene
HGNCHGNC:5985NCBI Gene23765GeneCardsIL17RA
Pharmacology
IUPHAR/GtoPdb1738KEGGhsa:23765
Structure
PDB3JVFPDB4HSAPDB4NUX
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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23GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-17 receptor A, how selective are they, and which programs against it are still in active trials?

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