Lysyl oxidase homolog 4

BE0018464ProteinHumansLOXL4

Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers. It is acted on by 1 drug in DrugBank.

Gene name
LOXL4
UniProtKB entry
Q96JB6Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
756 residues · 84,483 Da
Also known as
1.4.3.13 · LOXC · Lysyl oxidase-like protein 4 · Lysyl oxidase-related protein C

Resolves to

Protein
UniProtQ96JB6UniProt nameLOXL4_HUMAN
Gene
HGNCHGNC:17171NCBI Gene84171GeneCardsLOXL4
Pharmacology
KEGGhsa:84171
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which compounds in development act on Lysyl oxidase homolog 4, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In